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CNR: Alamanacco della Scienza


N. 16 - 15 dic 2010
ISSN 2037-4801

International info   a cura di Cecilia Migali


Scientists discover genes involved in puberty timing  

Researchers at Cnr-Institute of neurogenetics and neuropharmacology (Inn) have identified, as part of a large international collaboration, 30 new genes that control the age of sexual maturation in women. The paper, just published in Nature Genetics, found genes known to act on body weight regulation, thus finding the genetic components that explains the clinical correlation between early puberty and body fat. The other genes were involved in hormone regulation, cell development and other mechanisms linked to age at menarche (the onset of menstrual periods in women), and this shows that puberty timing is controlled by a complex range of biological processes.
To identify genes for age at menarche, scientists performed a meta-analysis of 32 genome-wide association studies in 87,802 women of European descent, with replication in up to 14,731 women.

Read the abstract


Fonte: Manuela Uda, Istituto di neurogenetica e neurofarmacologia, Lanusei, email manuela.uda@inn.cnr.it

Fonte: Serena Sanna, Istituto di neurogenetica e neurofarmacologia, Lanusei, tel. + 39 070 6754618, email serena.sanna@inn.cnr.it